By wangdepin
Computational-science methodology for Claude Code: research framing, pre-registration, reproducible analysis, anomaly investigation, and red-team review
Use when creating new skills, editing existing skills, or verifying skills work before deployment
Use after framing a question and before designing an analysis, or when choosing a method, judging whether a result is novel, or needing a prior effect size for a power calculation
Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions
Use when about to claim a result, effect, significance, or that an analysis reproduces, before reporting or writing it up - requires running the analysis fresh and reading the actual output first; evidence before claims always
Use when you have an approved research question and need a concrete analysis plan, before touching outcome data or fitting any model
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Science Superpowers is a complete computational-science methodology for your research agents, built on a set of composable skills plus initial instructions that make sure your agent actually uses them. It has zero third-party dependencies — it runs with only your agent harness and a POSIX shell.
⭐ If Science Superpowers helps your research, please star this repository. A star helps other scientists and engineers find the project and tells us the methodology is worth expanding.
Learn more: Introducing Science Superpowers — why we built it, the Iron Law, and the full workflow.
Stay up to date: Follow K-Dense on X, LinkedIn, and YouTube for new skills, release announcements, and research workflow demos.
It is a reimplementation of Superpowers (a software-development methodology) for a different domain: doing science with data. The architecture is the same — skills that auto-trigger via a session-start bootstrap — but the workflow is the research lifecycle, and the central discipline is pre-registration instead of test-driven development.
It starts the moment you fire up your agent. As soon as it sees you're trying to investigate something, it doesn't jump straight into running code on your data. Instead it steps back and helps you turn a fuzzy interest into a precise, falsifiable question.
Once the question is clear, it grounds the work in prior literature and standard methods, designs the analysis, and pre-registers the hypotheses, predictions, and decision rules before looking at the outcomes. That separation — confirmatory vs. exploratory, predictions locked before data — is what protects the work from p-hacking and HARKing (hypothesizing after results are known).
Then it executes the pre-registered plan in a reproducible workspace (pinned environment, fixed seeds, immutable raw data), investigates anomalies by root cause instead of quietly dropping inconvenient data, verifies every claim against fresh reproduced evidence, and red-teams the result before reporting it.
Because the skills trigger automatically, you don't need to do anything special. Your research agent just has Science Superpowers.
The agent checks for relevant skills before any task. Mandatory workflows, not suggestions.
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